Biochemistry

Department of Biochemistry

                    Biochemistry is the most fascinating subject as it deals with chemical language of life. No other subject has as much applications as biochemistry in the disciplines of medicine, health bioengineering and technology. The term biochemistry was introduced by Newberg in 1903. The scope of biochemistry is as vast as life itself. Every aspect of life, birth, growth, reproduction, aging and death involves biochemistry. Biochemistry is the most rapid developing and most innovative subject in medicine. This becomes evident from the fact that over the years, the major share of Nobel prizes earmarked for medicine and physiology has gone to researchers engaged in biochemistry.

Biochemistry research has amply demonstrated that all living things are closely related at the molecular level. Biochemistry is the subject of unity in the diversified living kingdom.

Advances in biochemistry have tremendous impact on human welfare and have largely benefited mankind and their living styles. These included the application of biochemistry in the laboratory for the diagnosis of diseases, the products (insulin, interferon, growth, hormones etc.) obtained from genetic engineering and the possible use of gene therapy in the near future.

Most of the diseases are manifestation of abnormalities of molecules, chemical reactions or biochemical processes. Hence, the major objective of teaching learning biochemistry is the complete understanding of the chemical process associated with living cells, at the molecular level. Undergraduate students of various streams such as MBBS and Nursing undergo training with emphasis on application or basic science in practice of their respective fields.

Electronic copies of books are made available to students of Ist MBBS which act as a tool for focused study of their textbook. In addition to this, frequent formative assessments are carried out for them. Moreover, chapter completion tests are carried out for their improvement in study.

In order to stimulate learning and improve communication skills of students, Department of biochemistry is conducting I-MBBS students seminar on various topics of applied and clinical biochemistry.

In addition to medical education, the department actively supports patients’ care by catering to ever increasing demands for various biochemical investigations. The laboratory is well equipped to provide various assays on patient samples. Moreover, the department is having a well-equipped research laboratory to conduct research and special investigations.

Faculty

Dr Annasaheb Yallappa Mane ( Professor & HOD)Ongoing research ProjectsResearch   

  • Study of isoenzymes in patients of thyroid diseases
  • Zende Prakash D. ( Assistant Professor )
  • Study of lipid metabolism genotypes and their correlation with biochemical markers in patients of Arteriosclerosis

Publications

Dr. Mane Annasaheb Y. (Professor & HOD)

  1. Mane A.Y, Bhagwat V.R. ,Borade V.B., Diabetic osteopenia: Relationship of Biochemical markers of bone metabolism and duration of illness- Journal of advance researches in biological sciences 2009,112 17 – 22
  2. A. Y, V.R.Bhagwat , G.G. Potey, Vaishali Mane, Common salt iodization status in urban areas of Ujjain (MP)-Oriental Journal of Chemistry vol.25(4) 1137-1140(2009)
  3. Mane A. Y, R. Bhagwat, Serum enzymes and liver function tests in thyroid disorders – Biomedicine,2011,31(4) :517-522
  4. Mane A. Y. , V. R. Bhagwat , Assessment of some biochemical markers of bone turnover in thyroid dysfunction state – Int .J. Pharm Bio Sci 2012 July 3(3) ;BZ 126 -133
  5. A. Y., Bhagwat V.R. , Mane S.D., A study of biochemical changes in occupational exposure of Portland segment among construction workers in Ujjain,(M.P.) –Indian journal of Public Health Research & Development, January – March 2013 vol.4 no-1

 

Mr. Zende Prakash D (Assistant Professor)

  1. Bhagwat VR, Subramanyam M, Zende PD: Erythrocyte Catalase, Plasma Ceruloplasmin activity and burn size in thermal injury. The antiseptic 2005: 102(6): 341-343.
  2. Kamble PS, Bhagwat VR, Padalkar RK, Zende PD, Patil SM: The Pattern of serum Bilirubin Level and comparison of Effectiveness of Phototherapy and Blood Exchange Transfusion in Neonatal Jaundice. Indian Medical Gazette 2005; 472-475.
  3. Padalkar RK, Kamble PS, Zende PD, Patil SM: Serum Lipid Peroxide and Trace Elements in Mental Disorders. The antiseptic 2007: 104(9): 452-453.
  4. Padalkar RK, Suryakar AN, Kamble PS, Zende PD, Patil SM, Pandhare VR: Oxidative stress and antioxidant ststus in pre-eclampsia and eclampsia: an application to forensic significance. Indian journal of Forensic Medicine and Pathology 2009: 2(1); 13-15
  5. D. Zende , P. D. Zende, V. R. Bhagwat, R. K. Padalkar, P. S. Kamble, S. M. Patil: Levels of trace elements in burn injury. The Antiseptic June 2010; 107(6): 288-290.
  6. Zende PD, Pujari KN, Jadkar SP: Antioxidants and trace elements in burns: International Journal of Pharma and Bio Sciences 2012: 3; 527-531.
  7. Kamble PS, Bankar MP, Zende PD, Trivedi D, Momin AA: Impact of Homocysteine, Folate and Vitamin B12 Levels in Patients of Arteriosclerosis. Research Journal of Pharmaceutical, Biological and Chemical Sciences 2013: 4(2); 344-348.
  8. Zende PD, Bankar MP, Kamble PS, Momin AA: Apolipoprotein E Gene Polymorphism And Its Effect On Plasma Lipids In Arteriosclerosis. Journal of Clinical and Diagnostic Research 2013. 7(10); 2149-2152.
  9. D. Zende, M. P. Bankar, A. A. Momin, P. S. Kamble: Study of Cetp I405v Genotype and its Association with Lipid Fractions in Myocardial Infarction Patients: A Case Control Study. Journal of Clinical and Diagnostic Research 2014. 8(6); CC01-CC04.

Dr.Sunil Kharge (Tutor)

  1. Sunil kharge, Dr. S. P. Dhonde, Dr. P. E. Jagtap, Dr. Nitin Nagne, Dr. G. J. Belvalkar.  “ Hypolipidemic effect of piper nigrum and zingiber officinale ( Mixed –Extract ) : An experimental study. International journal of current research, vol.7, Issue.09, PP. 20662-20670, September-2015.